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Lloyd Wei Tat Tang Selected Research

futibatinib

5/2022Quantification of the irreversible fibroblast growth factor receptor inhibitor futibatinib by UPLC-MS/MS: Application to the metabolic stability assay in human liver microsomes for the estimation of its in vitro hepatic intrinsic clearance.
1/2022Metabolic Activation of the Acrylamide Michael Acceptor Warhead in Futibatinib to an Epoxide Intermediate Engenders Covalent Inactivation of CYP3A.

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Lloyd Wei Tat Tang Research Topics

Disease

4Cholangiocarcinoma
05/2022 - 01/2021
3Hemorrhage
04/2022 - 06/2021
2Atrial Fibrillation
04/2022 - 06/2021
2Gout
01/2021 - 01/2021
1Mitochondrial Diseases (Mitochondrial Disease)
04/2022
1Hepatocellular Carcinoma (Hepatoma)
04/2022
1Venous Thromboembolism
01/2022
1Neoplasms (Cancer)
01/2022
1Stroke (Strokes)
06/2021
1Carcinoma (Carcinomatosis)
01/2021
1Massive Hepatic Necrosis
01/2021
1Urinary Bladder Neoplasms (Bladder Cancer)
11/2020

Drug/Important Bio-Agent (IBA)

3RivaroxabanIBA
04/2022 - 06/2021
3AnticoagulantsIBA
04/2022 - 06/2021
3Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
01/2022 - 01/2021
2futibatinibIBA
05/2022 - 01/2022
2Type 1 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 1)IBA
05/2022 - 01/2021
2Pharmaceutical PreparationsIBA
04/2022 - 01/2022
2DronedaroneFDA Link
04/2022 - 06/2021
2Amiodarone (Amiodarona)FDA LinkGeneric
04/2022 - 06/2021
2infigratinibIBA
01/2022 - 01/2021
2Uricosuric AgentsIBA
01/2021 - 01/2021
2BenzbromaroneIBA
01/2021 - 01/2021
1benzofuranIBA
04/2022
1Factor Xa (Coagulation Factor Xa)IBA
04/2022
1desethylamiodaroneIBA
04/2022
1N-desbutyldronedaroneIBA
04/2022
1poyendaroneIBA
04/2022
1FebuxostatFDA Link
04/2022
1Cytochrome P-450 CYP3AIBA
01/2021
1erdafitinibIBA
01/2021
1Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA
11/2020

Therapy/Procedure

1Therapeutics
11/2020